The most in important thing is to get your nitirtes to zero without doing this the treatment won't be very effective as you haven't dealt with the cause of their illness I would do two 50% water changes one in the morning and one in the evening to get your nitirtes as low as possible then I would do daily 50% water changes and add a double dose of prime I would stop feeding for a couple of days add some Aquarium salt that will help with nitirte poisoning 1table spoon for 2 gallons just remember to only put back in what you take out so if you do a 10 gallons water change put 5 table spoons of salt back in that will also help with the body sores