Prazipro dosed - then what?

[MDfish]

Cross posted on another forum, just looking to get the full extent of expertise. 

After a number of fish dieing off one by one over a period of a few months,  seems I have some sort of parasite. No symptoms outside of the dead fish.

Yesterday I dosed prazipro (20gallon). Just wait now and assume/hope it works? Dose again in 5 days?  I also ordered a couple other recommendations for meds I could try at the end of the prazipro window.

Thanks

[Guppysnail]

@Odd Duck has a detailed treatment outline and what to do step by step. @Colu has also shared that treatment. Scroll through the disease section and it’s been copied over in many threads. 

[MDfish]

Thanks. I also have Expel P and Paracleanse on the way so not sure if I should do one of those once the prazipro window is over.

[Guppysnail]

Here you go. I found @Odd Duck method 

Quote

Deworming

Siphon out debris from the bottom before and after dosing to remove any expelled worms, eggs, debris, etc.  Levamisole is inactivated by organic debris and by light, so dose after lights out and black out the tank for 24 hours, remove organics via water changes and cleaning the bottom of debris as much as possible.

It’s likely that levamisole does what it can do within the first hour, but best to follow directions precisely.  If you have a bare bottom hospital tank available, it might be best and easiest to transfer the fish to that tank for the duration of treatment - up to 5 weeks total treatment time if doing 3 doses of praziquantal.

Levamisole treatment should be weekly for 4 treatments.  Praziquantal treatment should be every other week (at least) for 2-3 treatments and it is left in for a week at a time.  It can be dosed the day after levamisole treatment.  Remove any carbon or Purigen from filters before dosing.

Have enough dechlorinated water to do a 50% water change immediately if any adverse symptoms are seen in the fish.

A typical treatment regimen: 

1. 50% water change with careful siphoning of debris from the bottom of the tank.

2. Dose with levamisole and black out the tank for 24 hours.  Then 50% water change siphoning the entire bottom of the tank.

3. Dose with praziquantal directly after the second 50% WC.

4. One week later, 50% water change siphoning the bottom thoroughly.  Dose with levamisole following directions in step 1-2.

5. One week later (start of week 3 of treatment), repeat all steps 1-4 over another 2 weeks time.

6. Repeat all steps 1-5, then do last WC one week later after third dose of praziquantal.

Not all snails will tolerate treatments, so best to remove any snails in the tank.

 

Condensed, weekly schedule:

Week 1: siphon debris and do 50% water change, levamisole x 24 hrs, siphon.  Treat with praziquantal and leave in until next week.

Week 2: siphon, levam x 24 hrs, siphon.

Week 3: siphon, levam x 24 hrs, siphon, then prazi.

Week 4: siphon, levam x 24 hrs, siphon.

Week 5: siphon, levam x 24 hrs, siphon, then prazi.

Week 6: siphon.

 

[MDfish]

Wow, super helpful. I guess because I did prazipro yesterday/first, my schedule will be slightly different but should get at the same thing.

Do I feed the fish the same during all of this? I normally only feed once a day (with one fast day a week) so overfeeding isn't an issue.

Nowhere to put my snails so I guess will just have to risk it with them. 

 

 

On 9/19/2023 at 11:40 AM, Guppysnail said:

Here you go. I found @Odd Duck method 

 

Quote

Deworming

Siphon out debris from the bottom before and after dosing to remove any expelled worms, eggs, debris, etc.  Levamisole is inactivated by organic debris and by light, so dose after lights out and black out the tank for 24 hours, remove organics via water changes and cleaning the bottom of debris as much as possible.

It’s likely that levamisole does what it can do within the first hour, but best to follow directions precisely.  If you have a bare bottom hospital tank available, it might be best and easiest to transfer the fish to that tank for the duration of treatment - up to 5 weeks total treatment time if doing 3 doses of praziquantal.

Levamisole treatment should be weekly for 4 treatments.  Praziquantal treatment should be every other week (at least) for 2-3 treatments and it is left in for a week at a time.  It can be dosed the day after levamisole treatment.  Remove any carbon or Purigen from filters before dosing.

Have enough dechlorinated water to do a 50% water change immediately if any adverse symptoms are seen in the fish.

A typical treatment regimen: 

1. 50% water change with careful siphoning of debris from the bottom of the tank.

2. Dose with levamisole and black out the tank for 24 hours.  Then 50% water change siphoning the entire bottom of the tank.

3. Dose with praziquantal directly after the second 50% WC.

4. One week later, 50% water change siphoning the bottom thoroughly.  Dose with levamisole following directions in step 1-2.

5. One week later (start of week 3 of treatment), repeat all steps 1-4 over another 2 weeks time.

6. Repeat all steps 1-5, then do last WC one week later after third dose of praziquantal.

Not all snails will tolerate treatments, so best to remove any snails in the tank.

 

Condensed, weekly schedule:

Week 1: siphon debris and do 50% water change, levamisole x 24 hrs, siphon.  Treat with praziquantal and leave in until next week.

Week 2: siphon, levam x 24 hrs, siphon.

Week 3: siphon, levam x 24 hrs, siphon, then prazi.

Week 4: siphon, levam x 24 hrs, siphon.

Week 5: siphon, levam x 24 hrs, siphon, then prazi.

Week 6: siphon.

 

 

[Colu]

On 9/20/2023 at 1:26 AM, MDfish said:

Wow, super helpful. I guess because I did prazipro yesterday/first, my schedule will be slightly different but should get at the same thing.

Do I feed the fish the same during all of this? I normally only feed once a day (with one fast day a week) so overfeeding isn't an issue.

Nowhere to put my snails so I guess will just have to risk it with them. 

 

 

 

Yes I would feed once a day during treatment