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Prazipro treatment for fluke


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I have read the praziquantel dissipates after 72hrs but the oxybispropanol takes 5-7 days. My question is: After adding prazipro, do I simply do a second dose after 5-7 days or do I do a massive water change first?

After the second dose, do I do a water change? Can I just let it dissipate? Currently, I am not running carbon in my fx4.



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